ncRNA name | hsa-miR-124a |
ncRNA Category | miRNA |
Disease name | uveal melanoma (UM) |
Species | Homo sapiens |
Tissues/Cell_line | UM samples and their adjacent uveal tissue counterparts; human UM cell lines M17, M21, M23 and SP6.5 |
Methods | qRT-PCR, methylation-specific PCR, CHIP assay, flow cytometry, transwell assay, Matrigel invasion assay, luciferase reporter assay, Western blot |
Expression pattern | down-regulated |
Functional description | miR-124a could function as a potent tumor suppressor by regulation of multiple targets, and was epigenetically silenced in the development of uveal melanoma. |
PubMed ID | 23404119 |
Year | 2013 |
Title | MicroRNA-124a is epigenetically regulated and acts as a tumor suppressor by controlling multiple targets in uveal melanoma. |
Drug-related ncRNA | NO |
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